[LMU-OSC News] Tomorrow: Talk by Lisa McShane: "Reproducibility of omics research: Shared responsibility and consequences of ignorance"

[LMU Open Science Center News]

*Reminder for tomorrow's talk by*

#Lisa McShane: "Reproducibility of omics research: Shared responsibility 
and consequences of ignorance"

A talk by the Acting Associate Director, Division of Cancer Treatment 
and Diagnosis, National Cancer Institute

The IBE, LMU Open Science Center, STRATOS, and the European Bioconductor 
Meeting cordially invite to a guest talk:

**When: December 5, 2018 - 5:00 pm s.t.**
**Where: Schellingstr. 3, Room S005**

*Abstract:*

Irreproducible biomedical research is particularly concerning because 
flawed findings have the potential to make their way to clinical studies 
involving human participants. Many factors have been suggested as 
contributors to irreproducible biomedical research, including poor study 
design, analytic instability of measurement methods, sloppy data 
handling, inappropriate and misleading statistical analysis methods, 
improper reporting or interpretation of results, and on rare occasions, 
outright scientific misconduct. Potential for these problems to occur is 
amplified when the research involves use of novel measurement 
technologies such as “omics assays” which generate large volumes of 
data requiring specialized expertise and computational approaches for 
proper management, analysis and interpretation 
[http://www.nationalacademies.org/hmd/Reports/2012/Evolution-of-Translational-Omics.aspx]. 
Successful translation of omics research findings to safe and effective 
clinical tests requires a research team with expertise including 
laboratory and clinical science, bioinformatics, computational science, 
and statistics. Team members share responsibility for ensuring that 
research is performed with integrity and best practices are followed to 
ensure reproducible results. Although making data and computer code 
publicly available are valuable and important first steps toward 
promoting reproducible research, they are not sufficient. Through a 
series of case studies, the many dimensions of reproducible omics 
research are explored, and shared responsibilities are discussed. 
Maintaining a culture of reproducible research requires effort, 
resources, and vigilance to counter many potential threats.

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http://www.osc.lmu.de/

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PD Dr. Felix Schönbrodt
Ludwig-Maximilians-Universität München, Germany

Managing Director of the LMU Open Science Center | http://www.osc.lmu.de
Psychological Methods and Assessment, Department Psychology | 
http://www.psy.lmu.de/pm_en/team/staff/schoenbrodt

http://www.nicebread.de
http://www.researchtransparency.org
Twitter: @nicebread303
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